Without a basic understanding of biology the possibilities for innovation that can change our lives and health become limited. We strive in each of our projects to open new spaces in basic biologic research that address fundamental questions about mechanisms in biology. We are developing new biological approaches and biotechnologies to open unexplored and understudied biological mechanisms.

To say ALS is a “devastating” neurodegenerative disease hardly covers it. It is relentless. There is no cure. There’s no therapy that can slow the progression of this disease. There’s not even bioassay to definitively diagnose the disease. More than 5000 patients are diagnosed with ALS in America each year. The average patient lives for three years following diagnosis. The death of motor neurons lead to continued paralysis and loss of muscle control, known as muscle atrophy.

That a link may exist between two completely unrelated pathologies, ALS and Ewing’s sarcoma, is a case of truth being stranger than fiction. Ewing’s sarcoma is the second most common pediatric bone cancer and diagnosed in more than 200 patients each year, mostly children.